| 翻訳と辞書 |
| ICE (chemotherapy) ： ウィキペディア英語版 |
ICE (chemotherapy)
ICE in the context of chemotherapy is an acronym for one of the chemotherapy regimens, used in salvage treatment of relapsed or refractory non-Hodgkin's lymphoma and Hodgkin lymphoma.
In case of CD20-positive B cell lymphoid malignancies the ICE regimen is often combined today with rituximab. This regimen is then called ICE-R or R-ICE or RICE.
()-ICE regimen consists of:
# (R)ituximab - an anti-CD20 monoclonal antibody, which is able to kill both normal and malignant CD20-bearing B cells;
# (I)fosfamide - an alkylating antineoplastic agent of the oxazafosforine group;
# (C)arboplatin - a platinum based drug, also with an alkylating mechanism;
# (E)toposide - a topoisomerase inhibitor.
== Dosing regimen ==
Cycles are repeated every 14 days for 3 cycles, then high-dose chemotherapy with autologous stem cell transplant follows (if the patient is considered eligible for HDCT and ASCT).〔(Ifosfamide, Carboplatin, and Etoposide: A Highly Effective Cytoreduction and Peripheral-Blood Progenitor-Cell Mobilization Regimen for Transplant-Eligible Patients With Non-Hodgkin’s Lymphoma )〕〔(Rituximab and ICE as second-line therapy before autologous stem cell transplantation for relapsed or primary refractory diffuse large B-cell lymphoma )〕
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
■ウィキペディアで「ICE (chemotherapy)」の詳細全文を読む
スポンサード リンク
| 翻訳と辞書 : 翻訳のためのインターネットリソース |
Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.
|
|